As in, you met a char, and it's a female toon, and you assigned a 'female' voice to that toon when she talked to you, and then knowing that he is actually a burly guy later, you still hear the female voice. Isn't that just weird? (Not the other player is 'weird', but that you feel weird for switching a 'she' and a 'he' in midsentence when referring to him/her, thinking about him/her. Or when talking about her with some other players). It gets confusing!
For someone that is used to work with imagination and play lots of paper rpg, that's perfectly normal. Whenever i see a female character, even if i know very well that beyound that there's a guy, i feel like having a chat with a nice female. In any case is unlikely that i'm going to meet the guy beyound the computer, and i'm playing with him/her brain, not the body!
In the last we are all part of the same race, the huge differences in the gender come from education.