Blind
If you cast it on a mob (which hasnt noticed you)- how is it able to run over to you and try to attack you? I thought it was blinded?
Root
Is really useful but almost to the extent of not needing melee- and to be fair meleers are having a hard enough time as it is (it seems melee is becoming obsolete in bigger battles)
Madness (this is important imho)
Does it really work? If so it would be great if in the afflicters sys info we could see "you make mob X hit itself for 500hp"
Slow Attack/Movement
To be honest i havent even tried using these much. I think they are kinda useless compared to the other spells (but thats my opinion)
I havent tested out the defensive ones- im hoping someone out there has some constructive criticism on them

My point about getting more info in the sys info box for madness i think could be applied to all of these spells. I chose madness cos i think this particularly applies