More hands bars - I've run out of space on all 10 of mine. Means I have to delete an old action every time I want to create a new one.
Guild List - I'm sure it can't be that hard to have it organize itself in some sort of fashion that meets common sense. Reverse alphabetical with a handful of random people thrown in here and there isn't helpful. Also the addition of the little friends list blue computer to the guild list would be a massive help.
Friends List - We have the computers to show when someones online. Could we have an additional symbol or something next to it to show when a person is AFK. Its a pain to type a giant tell to someone and then have it not get to the person since they're AFK.
NPC Bosses - As anyone whos attempted to kill Aen in the past couple months knows, shes had a major upgrade to both bodyguard staff and the fact shes unwilling to leave the comfort of her campfire. I'd like to see the return of the other 3, or at least bring back Lixie. I hear LoA killed her and she never came back. If they all got a massive upgrade like Aen/Lixie did, the challenge to kill them would still be there and there would be more options that the occaisonal attempt at killing Aen. It gets old getting DP in the same situation. I'd be more willing to try on a couple different bosses instead of the same ole "wow, that was a quick wipe"
Bosses/named - Make them harder. Yes, harder. There are level 260 named mobs that can be duo'd (or even solo'd if you have some time). Bosses can be trio'd still, even with the heal nerf. I'd love to see the higher level bosses (220+) get the same kind of boost Aen got. Beef up the guards, make the boss have more HP and do more damage. They are, after all, the strongest of their kind... so 4-5 homins should have A LOT of trouble taking them down.
Tryker Rite "Reward" - Zok beat me to it on this one, but please please please give us a way to turn this on/off. Just make it so we get an additional time brick to choose from or something. Its not much of a reward having my xp slowed down and not getting any additional mats from the source when diggin q250 (however, I can pull a full 29 from a source, Saranda

Don't believe 30 is possible since every time I try it gets stuck at 29.8 or something)
Crafting/Grinding/selling - While I would love a 'craft all' button, I don't think its going to happen. However, I think the selling part of grind stuff could be sped up a bit. Drag and drop in the merchants window or the ability to select multiple items would make emptying a bag of grind crafts much easier. as it is right now its click on item, wait for sell box to pop up, sell to npc, repeat. Takes forever and those who attempt to do it quickly often end up selling their amps.